Charge-shifting polyplex as a viral RNA extraction carrier for streamlined detection of infectious viruses-Reference-Cited by-同舟云学术

Charge-shifting polyplex as a viral RNA extraction carrier for streamlined detection of infectious viruses

Published:2023 Issue:10 Volume:10 Page:4571-4580
ISSN:2051-6347
Container-title:Materials Horizons
language:en
Short-container-title:Mater. Horiz.

Author:

Song Younseong¹,Song Jayeon²,Kim Seongeun¹,Jang Hyowon²,Kim Hogi¹,Jeong Booseok¹,Park Nahyun¹,Kim Sunjoo³,Yong Dongeun⁴,Lim Eun-Kyung²⁵⁶^ORCID,Lee Kyoung G.⁷,Kang Taejoon²⁶,Im Sung Gap¹^ORCID

Affiliation:

1. Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

2. Bionanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

3. Department of Laboratory Medicine, Gyeongsang National University College of Medicine, 79 Gangnam-ro, Jinju-si, Gyeongsangnam-do 52727, Republic of Korea

4. Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea

5. Department of Nanobiotechnology, KRIBB School of Biotechnology, University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea

6. School of Pharmacy, Sungkyunkwan University (SKKU), 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea

7. Division of Nano-Bio Sensors/Chips Development, National NanoFab Center (NNFC), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

Abstract

By harnessing its charge-shifting property, the polyplex-assisted qRT-PCR technique achieves efficient RNA capture and release. This innovation streamlines extraction & amplification in a one-pot process, offering rapid, user-friendly molecular diagnostics.

Funder

Ministry of Science and ICT, South Korea

Ministry of Trade, Industry and Energy

National NanoFab Center

Korea Research Institute of Bioscience and Biotechnology

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MH/D3MH00861D

Reference44 articles.