Enhancing the peroxidase-mimicking activity of hemin by covalent immobilization in polymer nanogels

Author:

Guo Jieyu12345,Liu Yuting12345ORCID,Zha Junqi12345,Han Honghua12345,Chen Yantao12345,Jia Zhongfan678910ORCID

Affiliation:

1. Shenzhen Key Laboratory of Environmental Chemistry and Ecological Remediation

2. College of Chemistry and Environmental Engineering

3. Shenzhen University

4. Shenzhen

5. China

6. Institute for Nanoscale Science and Technology

7. College of Science and Engineering

8. Flinders University

9. South Australia 5042

10. Australia

Abstract

A polymeric nanozyme that can closely mimic peroxidase is presented. The coordination between pendant hemins and primary amines together with the synergistic interactions between substrates and nanogels contribute to the enhanced catalytic activity.

Funder

Science and Technology Planning Project of Shenzhen Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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