Synthesis of 2-diphospho-myo-inositol 1,3,4,5,6-pentakisphosphate and a photocaged analogue-Reference-Cited by-同舟云学术

Synthesis of 2-diphospho-myo-inositol 1,3,4,5,6-pentakisphosphate and a photocaged analogue

Published:2016 Issue:24 Volume:14 Page:5559-5562
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pavlovic I.¹²³⁴,Thakor D. T.¹²³⁴,Jessen H. J.⁵⁶⁷⁸

Affiliation:

1. Department of Chemistry

2. University of Zürich

3. 8057 Zürich

4. Switzerland

5. Department of Chemistry and Pharmacy

6. Albert-Ludwigs University Freiburg

7. 79104 Freiburg

8. Germany

Abstract

Diphosphoinositol polyphosphates (inositol pyrophosphates, X-InsP₇) are a family of second messengers with important roles in eukaryotic biology. A new approach targeting 2-InsP₇ and a photocaged analogue is described.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00094K

Reference57 articles.

1. Inositol pyrophosphates: Why so many phosphates?

2. Inositol phosphate synthesis and the nuclear processes they affect

3. Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain

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