Cu-catalyzed cyanomethylation of imines and α,β-alkenes with acetonitrile and its derivatives

Author:

Ahmad Muhammad Siddique1234ORCID,Ahmad Atique5674

Affiliation:

1. Institute of Chemical Sciences

2. Bahauddin Zakariya Unversity

3. Multan

4. Pakistan

5. Department of Physical Sciences

6. Air University

7. Islamabad Campus

Abstract

We describe copper-catalyzed cyanomethylation of imines and α,β-alkenes with a methylnitrile source and provide an efficient route to synthesize arylacrylonitriles and β,γ-unsaturated nitriles.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference87 articles.

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3. Recent developments and perspectives in palladium-catalyzed cyanation of aryl halides: synthesis of benzonitriles

4. Recent advances in C–CN and C–H bond activation of green nitrile (MeCN) for organo-complexation, cyanation and cyanomethylation

5. A Facile Synthesis of 1,5-Dienes and β,γ-Unsaturated Nitriles via Trityl Perchlorate-Catalyzed Allylation

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