Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers-Reference-Cited by-同舟云学术

Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers

Published:2017 Issue:32 Volume:5 Page:6546-6556
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Trinh Thi Minh Nguyet¹²³⁴⁵,Holler Michel¹²³⁴⁵,Schneider Jérémy P.⁶²³⁴⁵,García-Moreno M. Isabel⁷⁸⁹¹⁰¹¹^ORCID,García Fernández José M.¹²¹³¹⁴¹¹^ORCID,Bodlenner Anne⁶²³⁴⁵,Compain Philippe⁶²³⁴⁵^ORCID,Ortiz Mellet Carmen⁷⁸⁹¹⁰¹¹^ORCID,Nierengarten Jean-François¹²³⁴⁵^ORCID

Affiliation:

1. Laboratoire de Chimie des Matériaux Moléculaires

2. Université de Strasbourg et CNRS (UMR 7509)

3. Ecole Européenne de Chimie

4. Polymères et Matériaux

5. 67087 Strasbourg Cedex 2

6. Laboratoire de Synthèse Organique et Molécules Bioactives

7. Department of Organic Chemistry

8. Faculty of Chemistry

9. University of Sevilla

10. 41011 Sevilla

11. Spain

12. Instituto de Investigaciones Químicas (IIQ)

13. CSIC – Universidad de Sevilla

14. E-41092 Sevilla

Abstract

A dramatic enhancement in the glycosidase multivalent inhibitory effect was observed while going from a dodecavalent iminosugar ball to the corresponding giant molecule with 120 peripheral subunits.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TB/C7TB01052D

Reference106 articles.

1. Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands

2. Multivalent glycoconjugate syntheses and applications using aromatic scaffolds

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5. Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters, -glycopolymers and -glycoassemblies

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