Synthesis and characterization of new 1,3,4-thiadiazole derivatives: study of their antibacterial activity and CT-DNA binding

Author:

Sayiner Hakan S.1,Yilmazer Mehmet I.2ORCID,Abdelsalam Aisha. T.3,Ganim Mohamed A.3,Baloglu Cengiz3,Altunoglu Yasemin Celik3,Gür Mahmut4ORCID,Saracoglu Murat2,Attia Mohamed S.5ORCID,Mahmoud Safwat A.6,Mohamed Ekram H.7ORCID,Boukherroub Rabah8,Al-Shaalan Nora Hamad9ORCID,Alharthi Sarah10ORCID,Kandemirli Fatma11,Amin Mohammed A.10ORCID

Affiliation:

1. Department of Infectious Diseases, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey

2. Faculty of Education, Erciyes University, 38039, Kayseri, Turkey

3. Department of Genetic & Bioengineering, Faculty of Engineering & Architecture, Kastamonu University, 37150, Kastamonu, Turkey

4. Department of Forest Industrial Engineering, Faculty of Forestry, Kastamonu University, 37150, Kastamonu, Turkey

5. Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt

6. Physics Department, Faculty of Science, Northern Border University, Arar, Saudi Arabia

7. Department of Analytical Chemistry, Faculty of Pharmacy, The British University in Egypt, 11837, El-Sherouk City, Egypt

8. Univ. Lille, CNRS, Centrale Lille, Univ. Polytechnique Hauts-de-France, UMR 8520 – IEMN, F59000 Lille, France

9. Department of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

10. Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia

11. Department of Biomedical Engineering, Faculty of Engineering and Architecture, Kastamonu University, 37150, Kastamonu, Turkey

Abstract

1,3,4-Thiadiazole molecules showed an inhibitory effect for the Staphylococcus epidermidis protein.

Funder

Princess Nourah Bint Abdulrahman University

Ministry of Education – Kingdom of Saudi Arabi

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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