Aryl ethynyl anthraquinones: a useful platform for targeting telomeric G-quadruplex structures
Author:
Affiliation:
1. Dipartimento di Chimica
2. Università di Pavia
3. Pavia, Italy
4. Department of Pharmaceutical and Pharmacological Sciences
5. 35131 Padova, Italy
6. Dipartimento di Scienze della Salute
7. Universitá di Catanzaro
8. 88100 Catanzaro, Italy
Abstract
2,7-Diaryl ethynyl anthraquinones have been synthesized by Sonogashira cross-coupling and evaluated as telomeric G-quadruplex ligands, with good G-quadruplex/duplex selectivity.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00220B
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