K2S2O8-promoted direct thiocyanation of pyrazolin-5-ones with ammonium thiocyanate at room temperature

Author:

Mao Xiaokang12345,Ni Jiabin678910,Xu Bin12345ORCID,Ding Chunyong678910ORCID

Affiliation:

1. Department of Chemistry

2. Innovative Drug Research Center

3. School of Materials Science and Engineering

4. Shanghai University

5. Shanghai 200444

6. CAS Key Laboratory of Receptor Research

7. and the State Key Laboratory of Drug Research

8. Shanghai Institute of Materia Medica (SIMM)

9. Chinese Academy of Sciences

10. Shanghai 201203

Abstract

A facile and efficient approach for the direct thiocyanation of pyrazolin-5-ones under mild conditions has been established for the first time.

Funder

Chinese Academy of Sciences

National Natural Science Foundation of China

National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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