Palladium-catalyzed asymmetric allylic alkylation of 3-aminooxindoles to access chiral homoallylic aminooxindoles
Author:
Affiliation:
1. Key Laboratory of Biocatalysis & Chiral Drug Synthesis of Guizhou Province
2. School of Pharmacy
3. Zunyi Medical University
4. Zunyi 563000
5. China
Abstract
An organometal catalytic conversion of 3-aminooxindoles for the diastereo- and enantioselective synthesis of homoallylic aminooxindoles has been described.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00550B
Reference60 articles.
1. Pyrrolidinyl-Spirooxindole Natural Products as Inspirations for the Development of Potential Therapeutic Agents
2. Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position
3. Recent progress in enantioselective synthesis of C3-functionalized oxindoles: rare earth metals take action
4. Organocatalytic asymmetric synthesis of 3-amino-2-oxindole derivatives bearing a tetra-substituted stereocenter
5. A Journey in the Catalytic Synthesis of 3-Substituted 3-Aminooxindoles
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1. Sustainable and selective Ni-catalyzed allylation of 2-oxindoles and 2-coumaranones in batch and flow chemistry;Reaction Chemistry & Engineering;2023
2. Asymmetric Allylic Alkylation and Related Reactions;Reference Module in Chemistry, Molecular Sciences and Chemical Engineering;2022
3. Palladium-catalyzed asymmetric allylic alkylation of 3-amino-2-oxindoles: Synthesis of 3-allyl-3-amino-2-oxindoles;Tetrahedron Letters;2021-10
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