Abietane diterpenoids from Caryopteris incana (Thunb.) Miq.
Author:
Affiliation:
1. Institute of Chinese Materia Medica
2. Shanghai University of Traditional Chinese Medicine
3. Shanghai 201203
4. China
5. College of Pharmacy Anhui University of Traditional Chinese Medicine
6. Hefei 230031
Abstract
12 new diterpenes including 4 new rearranged abietanes caryopincaolide A–D with unprecedented skeletons have been isolated, together with 28 known diterpenes. Some possess DPP-IV inhibitory effects, several also exhibit significant levels of cytotoxicity, and one shows induction of apoptosis in Hey and A-549 cells.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00139D
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