Eco-friendly polyethylene glycol (PEG-400): a green reaction medium for one-pot, four-component synthesis of novel asymmetrical bis-spirooxindole derivatives at room temperature
Author:
Affiliation:
1. Department of Chemistry
2. Faculty of Sciences
3. Persian Gulf University
4. Bushehr
5. Iran
Abstract
PEG-400 has been used for the synthesis of novel asymmetrical bis-spirooxindoles by the reaction of N-alkyl isatin, isatin derivatives, alkylmalonates and C–H activated carbonyl compounds in the presence of K2CO3 at room temperature.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA13133J
Reference33 articles.
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3. Poly(ethylene glycol) (PEG) as a Reusable Solvent Medium for Organic Synthesis. Application in the Heck Reaction
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