Spacer-enhanced chymotrypsin-activated peptide-functionalized gold nanoparticle probes: a rapid assay for the diagnosis of pancreatitis

Author:

Yeh Fang-Yuan123,Tseng I-Hua123,Chuang Shu-Hung12345,Lin Chih-Sheng123

Affiliation:

1. Department of Biological Science and Technology

2. National Chiao Tung University

3. Hsinchu 300, Taiwan

4. Department of Surgery

5. Mackay Memorial Hospital

Abstract

A spacer-enhanced FITC-labeled peptide self-assembled onto AuNPs was fabricated as a chymotrypsin activated fluorescent AuNP probe and was used for the diagnosis of pancreatitis with fecal specimens.

Funder

National Science Council Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference44 articles.

1. L. Goldman , A. I. Schafer and R. L. F.Cecil , Goldman’s Cecil Medicine , Elsevier/Saunders , Philadelphia , 24 edn, 2012 , pp. 937–944

2. Early Events in Acute Pancreatitis

3. Diagnosis of pancreatitis

4. The Role of Routine Assays of Serum Amylase and Lipase for the Diagnosis of Acute Abdominal Pain

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