Differences in cisplatin distribution in sensitive and resistant ovarian cancer cells: a TEM/NanoSIMS study

Author:

Lee Ronald F. S.123,Riedel Tina123,Escrig Stéphane4523,Maclachlan Catherine623,Knott Graham W.623,Davey Curt A.789108,Johnsson Kai123,Meibom Anders452311,Dyson Paul J.123ORCID

Affiliation:

1. Institute of Chemical Sciences and Engineering, Ecole Polytechnique Fédérale de Lausanne (EPFL)

2. CH-1015 Lausanne

3. Switzerland

4. Laboratory for Biological Geochemistry

5. Ecole Polytechnique Fédérale de Lausanne (EPFL)

6. Interdisciplinary Centre for Electron Microscopy, Ecole Polytechnique Fédérale de Lausanne (EPFL)

7. School of Biological Sciences

8. Nanyang Technological University

9. Singapore 637551

10. NTU Institute of Structural Biology

11. Center for Advanced Surface Analysis

Abstract

Cisplatin is a widely used anti-cancer drug, but its effect is often limited by acquired resistance to the compound during treatment.

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Reference42 articles.

1. Platinum Compounds: a New Class of Potent Antitumour Agents

2. SEER Cancer Statistics Review 1975-2008-Previous Version – SEER Cancer Statistics, http://seer.cancer.gov/archive/csr/1975_2008/ , (accessed June 13, 2016)

3. Cisplatin | MIMS online, http://www.mims.co.uk/drugs/cancer/antineoplastics/cisplatin , (accessed April 4, 2016)

4. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs

5. Third row transition metals for the treatment of cancer

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3