Photoredox synthesis of functionalized quinazolines via copper-catalyzed aerobic oxidative Csp2–H annulation of amidines with terminal alkynes-Reference-Cited by-同舟云学术

Photoredox synthesis of functionalized quinazolines via copper-catalyzed aerobic oxidative Csp2–H annulation of amidines with terminal alkynes

Published:2021 Issue:14 Volume:23 Page:5024-5030
ISSN:1463-9262
Container-title:Green Chemistry
language:en
Short-container-title:Green Chem.

Author:

Charpe Vaibhav Pramod¹²³⁴^ORCID,Ragupathi Ayyakkannu¹²³⁴,Sagadevan Arunachalam¹²³⁴^ORCID,Hwang Kuo Chu¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. National Tsing Hua University

3. Hsinchu

4. Republic of China

Abstract

We demonstrate a simple CuCl-catalyzed C–H annulation of amidines with terminal alkynes to form functionalized quinazolines at RT. This photochemical method is a mild process, highly efficient, and practically applicable to the synthesis of anticancer agents.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/GC/D1GC01493E

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