Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response-Reference-Cited by-同舟云学术

Hydrogel 3D in vitro tumor models for screening cell aggregation mediated drug response

Published:2020 Issue:7 Volume:8 Page:1855-1864
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Monteiro Maria V.¹²³⁴⁵,Gaspar Vítor M.¹²³⁴⁵^ORCID,Ferreira Luís P.¹²³⁴⁵,Mano João F.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. CICECO – Aveiro Institute of Materials

3. University of Aveiro

4. Aveiro

5. Portugal

Abstract

Hydrogel-based 3D in vitro models comprising tumor ECM-mimetic biomaterials exhibit differential responses to therapeutics according to cancer cells cellular aggregation state.

Funder

H2020 European Research Council

Fundação para a Ciência e a Tecnologia

Ministério da Educação e Ciência

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/C9BM02075F

Reference46 articles.

1. Bioengineering-inspired three-dimensional culture systems: Organoids to create tumor microenvironment

2. Three-dimensional cell culture: the missing link in drug discovery

3. 3D tumour models: novel in vitro approaches to cancer studies

4. The third dimension bridges the gap between cell culture and live tissue

5. Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

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