Controlling ring-chain tautomerism through steric hindrance
Author:
Affiliation:
1. Dpto. Química Inorgánica
2. Fac. Química
3. Univ. Santiago de Compostela
4. Santiago de Compostela
5. Spain
Abstract
Adequate substituents can favour/hinder, the tautomerisation of Schiff bases into tetrahydroquinazolines, by means of strong/weak H bonds.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA10132H
Reference27 articles.
1. Tautomeric Equilibria in Relation to Pi-Electron Delocalization
2. Synthesis and antitumor activity of some 2, 3-disubstituted quinazolin-4(3H)-ones and 4, 6- disubstituted- 1, 2, 3, 4-tetrahydroquinazolin-2H-ones
3. De novo design, synthesis and biological evaluation of 1,4-dihydroquinolin-4-ones and 1,2,3,4-tetrahydroquinazolin-4-ones as potent kinesin spindle protein (KSP) inhibitors
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