Nucleophilic halo-Michael addition under Lewis-base activation

Author:

Laina-Martín Víctor12345ORCID,Pérez Ignacio12345,Fernández-Salas Jose A.12345ORCID,Alemán José12345ORCID

Affiliation:

1. Organic Chemistry Department

2. Módulo 1

3. Universidad Autónoma de Madrid

4. 28049 Madrid

5. Spain

Abstract

A simple and general conjugate nucleophilic halogenation is presented. In addition, a straightforward diastereoselective halogen installation using α,β-unsaturated acyloxazolidinones as platforms has been developed.

Funder

Comunidad de Madrid

Universidad Autónoma de Madrid

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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3. Cross-Coupling Reactions, Workbench , ed. G. A. Molander , M. Larhed and J. Wolfe , Science of Synthesis Series, Thieme Chemistry , Stuttgart , 2013

4. Cross Coupling Reactions in Organic Synthesis Themed Issue , Chem. Soc. Rev. , 2011 , 40 , 4877

5. F.-A. Carey and R.-J.Sundberg , Advanced Organic Chemistry, Part B: Reaction and Synthesis , Springer , New York, NY, USA , 5th edn, 2007 , p. 217

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