Towards predictive control of reversible nanoparticle assembly with solid-binding proteins

Author:

Cai Yifeng1,Qi Xin1,Boese Julia1,Zhao Yundi1,Hellner Brittney1,Chun Jaehun23ORCID,Mundy Christopher J.12ORCID,Baneyx François1ORCID

Affiliation:

1. Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, USA

2. Physical and Computational Sciences Directorate, Pacific Northwest National Laboratory, Richland, Washington 99354, USA

3. Levich Institute and Department of Chemical Engineering, CUNY City College of New York, New York, New York 10031, USA

Abstract

We combine multiscale modeling with solution and protein engineering to derive design principles for controlling growth and fragmentation pathways in stimuli-responsive protein-nanoparticle assemblies.

Funder

Energy Frontier Research Centers

Basic Energy Sciences

Publisher

Royal Society of Chemistry (RSC)

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