Metal-free electrochemistry promoted radical cascade cyclization to access CF3-containing benzimidazo[2,1-a]isoquinolin-6(5H)-ones-Reference-Cited by-同舟云学术

Metal-free electrochemistry promoted radical cascade cyclization to access CF₃-containing benzimidazo[2,1-a]isoquinolin-6(5H)-ones

Published:2023 Issue:33 Volume:21 Page:6715-6718
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Changjun¹,Yu Zhichen¹,Ding Yuxin¹,Shi Yuan¹,Xie Yuanyuan¹²³^ORCID

Affiliation:

1. College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, China

2. Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, Zhejiang University of Technology, Hangzhou, 310014, China

3. Key Laboratory for Green Pharmaceutical Technologies and Related Equipment of Ministry of Education, Key Laboratory of Pharmaceutical Engineering of Zhejiang Province, Hangzhou, 310014, China

Abstract

Using CF3SO2Na as the CF3 radical source, an eco-friendly approach for electrochemistry-mediated radical cascade cyclization of N-methacryloyl-2-phenylbenzoimidazoles was described.

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00854A

Reference29 articles.

1. Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents