2-(2-(Pyren-1-yl)-1H-benzo[d]imidazol-1-yl)-ethyl-4-methyl benzenesulfonate (PBITS) and its application for determination of bile acids by HPLC-FLD-MS

Author:

Xia Lian1234,Wu Chuanxiang1234,Sun Zhiwei1234,You Jinmao12345

Affiliation:

1. The Key Laboratory of Life-Organic Analysis

2. College of Chemistry Science

3. Qufu Normal University

4. Qufu Shandong, P. R. China

5. Northwest Plateau Institute of Biology

Abstract

A method of high performance liquid chromatography-fluorescence detection-mass spectrometry identification coupled with pre-column derivatization to determine bile acids from bio-sample has been developed here.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference42 articles.

1. Simultaneous analysis and retention behavior of the glucuronide, glucoside, and N-acetylglucosaminide conjugates of bile acids in conventional and inclusion high-performance liquid chromatographic methods

2. The Importance of Serum Bile Acid Level Analysis and Treatment With Ursodeoxycholic Acid in Intrahepatic Cholestasis of Pregnancy

3. Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease

4. I. M. Yousef , G.Bouchard , B.Tuchweber and G. L.Plaa , in Toxicology of the Liver , G. L. Plaa and W. R. Hewitt , Taylor & Francis , New York , 2nd edn, 1998 , pp. 347–382

5. J. D. Ostrow , in Hepatic Transport and Bile Secretion: Physiology and Pathophysiology , ed. N. Tavolini and P. D. Berk , Raven Press , New York , 1993 , pp. 673–712

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