On-chip-angiogenesis based on a high-throughput biomimetic three-dimensional cell spheroid culture system

Author:

Wang Yachao12,Zeng Xuemei1,Chen Peng1,Du Wei1ORCID,Pei Yumei3,Wang Guoping1,Liu Bi-Feng1

Affiliation:

1. The Key Laboratory for Biomedical Photonics of MOE at Wuhan National Laboratory for Optoelectronics-Hubei Bioinformatics & Molecular Imaging Key Laboratory, Systems Biology Theme, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China

2. Department of Ultrasound, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

3. Department of Pharmacy, Wuxi People's Hospital Attached to Nanjing Medical University, Wuxi 214023, China

Abstract

Angiogenesis is one of the most essential developmental processes and plays a key role in organogenesis and tumorigenesis in which epithelial cells proliferate and migrate, thus resulting in sprouting and extension of the existing vasculature.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Natural Science Foundation of Henan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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