Molecular rotors report on changes in live cell plasma membrane microviscosity upon interaction with beta-amyloid aggregates-Reference-Cited by-同舟云学术

Molecular rotors report on changes in live cell plasma membrane microviscosity upon interaction with beta-amyloid aggregates

Published:2018 Issue:46 Volume:14 Page:9466-9474
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Kubánková Markéta¹²³⁴^ORCID,López-Duarte Ismael¹²³⁴^ORCID,Kiryushko Darya⁵⁶⁷⁴⁸^ORCID,Kuimova Marina K.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Imperial College London

3. London SW7 2AZ

4. UK

5. Department of Materials and London Center for Nanotechnology

6. Imperial College

7. SW72AZ London

8. Centre for Neuroinflammation and Neurodegeneration

Abstract

Viscosity-sensing fluorophores termed molecular rotors were used to investigate the microviscosity of plasma membranes of live cells upon interaction with oligomeric and fibrillar forms of beta-amyloid Aβ(1–42).

Funder

Engineering and Physical Sciences Research Council

Michael J. Fox Foundation for Parkinson's Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SM/C8SM01633J

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5. Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

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