An enzyme-activatable probe liberating AIEgens: on-site sensing and long-term tracking of β-galactosidase in ovarian cancer cells-Reference-Cited by-同舟云学术

An enzyme-activatable probe liberating AIEgens: on-site sensing and long-term tracking of β-galactosidase in ovarian cancer cells

Published:2019 Issue:2 Volume:10 Page:398-405
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Gu Kaizhi¹²³⁴⁵,Qiu Wanshan⁶⁷⁸⁹,Guo Zhiqian¹²³⁴⁵^ORCID,Yan Chenxu¹²³⁴⁵,Zhu Shiqin¹²³⁴⁵,Yao Defan¹²³⁴⁵,Shi Ping¹⁰¹¹¹²⁹^ORCID,Tian He¹²³⁴⁵,Zhu Wei-Hong¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory of Functional Materials Chemistry

2. Key Laboratory for Advanced Materials and Institute of Fine Chemicals

3. Joint International Research Laboratory of Precision Chemistry and Molecular Engineering

4. Feringa Nobel Prize Scientist Joint Research Center

5. School of Chemistry and Molecular Engineering

6. Department of Cardiothoracic Surgery

7. Children's Hospital of Fudan University

8. Shanghai 201102

9. China

10. State Key Laboratory of Bioreactor Engineering

11. East China University of Science & Technology

12. Shanghai 200237

Abstract

We describe an enzyme-regulated liberation strategy to in situ generate AIEgen nanoaggregates for on-site sensing and long-term tracking of β-galactosidase in ovarian cancer cells.

Funder

National Natural Science Foundation of China

State Key Laboratory of Bioreactor Engineering

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C8SC04266G

Reference58 articles.

1. Long-term tracking of cells using inorganic nanoparticles as contrast agents: are we there yet?

2. In Situ Localization of Enzyme Activity in Live Cells by a Molecular Probe Releasing a Precipitating Fluorochrome