One-pot three-component domino protocol for the synthesis of novel pyrano[2,3-d]pyrimidines as antimicrobial and anti-biofilm agents

Author:

Suresh Lingala1234,Poornachandra Y.5674,Kanakaraju S.1234,Ganesh Kumar C.5674,Chandramouli G. V. P.1234

Affiliation:

1. Department of Chemistry

2. National Institute of Technology

3. Warangal 506 004

4. India

5. Medicinal Chemistry and Pharmacology Division

6. CSIR-Indian Institute of Chemical Technology

7. Hyderabad 500 007

Abstract

A simple and facile synthesis of a series of novel pyrano[2,3-d]pyrimidines have been achieved successfullyviaone-pot three-component reaction of 2-amino-7-methyl-5-oxo-4-phenyl-4,5-dihydropyrano[4,3-b]pyran-3-carbonitriles, DMF-DMA and arylamines.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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