Kinetic and density functional theory (DFT) studies of in vitro reactions of acrylamide with the thiols: captopril, l-cysteine, and glutathione

Author:

Bent Grace-Anne1234,Maragh Paul1254,Dasgupta Tara1254,Fairman Richard A.1234,Grierson Lebert1234

Affiliation:

1. Department of Chemistry

2. The University of the West Indies

3. St. Augustine

4. West Indies

5. Kingston 7

Abstract

In vitro kinetic studies with DFT computations to explain the potential of acrylamide metabolism/toxicity with thiols in vivo.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Reference45 articles.

1. Office of Environmental Health Hazard Assessment (O.E.H.H.A.) California Environmental Protection Agency, Meeting of the Carcinogen Identification Committee (CIC). Safe drinking water and toxic enforcement act of 1986 (proposition 65), http://www.oehha.ca.gov/prop65/docs_state/pdf/acrylbrief.pdf, Access Date: July 12, 2014

2. Acrylamide: A Cooking Carcinogen?

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