Delivery of dual miRNA through CD44-targeted mesoporous silica nanoparticles for enhanced and effective triple-negative breast cancer therapy
Author:
Affiliation:
1. Center for Research in Nanoscience and Nanotechnology
2. Technology Campus
3. University of Calcutta
4. Kolkata 700106
5. India
6. Department of Physiology
7. Kolkata
8. Amity School of Biotechnology
9. Amity University
Abstract
Cationic Mesoporous silica Nanoparticle coated with hyaluronic acid conjugated polymer (HA-Dual miRNA Np) facilitated enhanced dual miRNA loading, efficient delivery and significantly inhibited tumor growth as well as retarded metastasis in triple-negative breast cancer.
Funder
Department of Science and Technology
Council of Scientific and Industrial Research
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00015A
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