TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide–alkyne cycloaddition reactions
Author:
Affiliation:
1. Cristal Therapeutics
2. 6229 EV Maastricht
3. The Netherlands
4. Mercachem
5. 6546 BB Nijmegen
6. The Maastricht Multimodal Molecular Imaging Institute (M4I)
7. Maastricht University
8. 6229 ER Maastricht
9. Department of Biochemistry
10. CARIM
Abstract
TMTHSI was developed as new reagent for strain-promoted azide–alkyne cycloaddition reactions, enabling connection of a diversity of small to large molecular constructs.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC03477K
Reference34 articles.
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2. Cu-Catalyzed Azide−Alkyne Cycloaddition
3. Development and Applications of the Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC) as a Bioorthogonal Reaction
4. Click Chemistry in Peptide-Based Drug Design
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