Effects of guanidino modified aminoglycosides on mammalian membranes studied using a quartz crystal microbalance-Reference-Cited by-同舟云学术

Effects of guanidino modified aminoglycosides on mammalian membranes studied using a quartz crystal microbalance

Published:2017 Issue:5 Volume:8 Page:1112-1120
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

John Torsten¹²³⁴⁵^ORCID,Voo Zhi Xiang¹²³⁴,Kubeil Clemens¹²³⁴,Abel Bernd⁵⁶⁷⁸,Graham Bim⁹¹⁰²¹¹⁴,Spiccia Leone¹²³⁴,Martin Lisandra L.¹²³⁴^ORCID

Affiliation:

1. School of Chemistry

2. Monash University

3. Clayton

4. Australia

5. Leibniz Institute of Surface Modification, and Wilhelm-Ostwald-Institute for Physical and Theoretical Chemistry

6. Leipzig University

7. 04318 Leipzig

8. Germany

9. Medicinal Chemistry

10. Monash Institute of Pharmaceutical Sciences

11. Parkville

Abstract

Drug-delivery of aminoglycosides was studied using the biophysical platform of a quartz crystal microbalance. Guanidino modification enhanced the biomolecule-membrane interaction.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/MD/C7MD00054E

Reference67 articles.

1. The Targets of Currently Used Antibacterial Agents: Lessons for Drug Discovery

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