Biomimetic polysaccharide-cloaked lipidic nanovesicles/microassemblies for improving the enzymatic activity and prolonging the action time for hyperuricemia treatment-Reference-Cited by-同舟云学术

Biomimetic polysaccharide-cloaked lipidic nanovesicles/microassemblies for improving the enzymatic activity and prolonging the action time for hyperuricemia treatment

Published:2020 Issue:28 Volume:12 Page:15222-15235
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Yang Lan¹²³⁴,Zhang Yonghong¹²³⁴,Xie Jiangchuan¹²³⁴,Zhong Cailing¹²³⁴,He Dan¹²³⁴,Wang Tingting⁵⁶²⁷⁴^ORCID,Li Kailing¹²³⁴,Li Yao⁸⁹¹⁰⁴,Shi Da¹¹¹²¹³¹⁴,Abagyan Ruben¹¹¹²¹³¹⁴,Yang Lin¹⁵¹⁶⁷⁴,Zhang Jingqing¹²³⁴^ORCID

Affiliation:

1. Chongqing Research Center for Pharmaceutical Engineering

2. Chongqing Medical University

3. Chongqing 400016

4. China

5. Biochemistry and Molecular Biology Laboratory

6. Experimental Teaching and Management Center

7. Chongqing 401331

8. Division of Infectious Disease

9. Chongqing Public Health Medical Center

10. Chongqing 400036

11. Skaggs School of Pharmacy and Pharmaceutical Sciences

12. University of California San Diego

13. La Jolla

14. USA

15. Department of Pharmacology

16. Chongqing Medical and Pharmaceutical College

Abstract

We prepare biomimetic polysaccharide hyaluronan-cloaked lipidic nanovesicles/microassemblies by entrapping uricase in the core of the hollow vesicles or by tethering them to the surfaces and then perform an antihyperuricemia evaluation of them.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Chongqing

Venture and Innovation Support Program for Chongqing Overseas Returnees

Chongqing Municipal Education Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR02651D

Reference47 articles.