1,4-Dithiothreitol mediated cleavage of the acetal and ketal type of diol protecting groups-Reference-Cited by-同舟云学术

1,4-Dithiothreitol mediated cleavage of the acetal and ketal type of diol protecting groups

Published:2018 Issue:16 Volume:5 Page:2427-2431
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Yan¹²³⁴⁵,Zeng Jing¹²³⁴⁵^ORCID,Sun Jiuchang¹²³⁴⁵,Cai Lei¹²³⁴⁵,Zhao Yueqi¹²³⁴⁵,Fang Jing¹²³⁴⁵,Hu Bo¹²³⁴⁵,Shu Penghua¹²³⁴⁵,Meng Lingkui¹²³⁴⁵,Wan Qian¹²³⁴⁵^ORCID

Affiliation:

1. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation

2. School of Pharmacy

3. Huazhong University of Science and Technology

4. Wuhan

5. China

Abstract

An efficient deprotection of the ketal and acetal type protecting groups has been achieved with Brønsted acid as a catalyst and 1,4-dithiothreitol as a ketal or acetal exchange reagent.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00247A

Reference43 articles.

1. P. G. M. Wuts and T. W.Greene , Protective Groups in Organic Synthesis , John Wiley and Sons , New York , 4th edn, 2007

2. P. J. Kocienski , Protecting Groups , Georg Thieme Verlag , Stuttgart , 3rd edn, 2005