Field-effect transistor antigen/antibody-TMDs sensors for the detection of COVID-19 samples-Reference-Cited by-同舟云学术

Field-effect transistor antigen/antibody-TMDs sensors for the detection of COVID-19 samples

Published:2023 Issue:9 Volume:15 Page:4570-4580
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Canton-Vitoria Ruben¹²^ORCID,Sato Kotaro³⁴,Motooka Yashiro³,Toyokuni Shinya³,Liu Zheng⁵^ORCID,Kitaura Ryo¹⁶^ORCID

Affiliation:

1. Department of Chemistry, Nagoya University, Nagoya, Aichi 464-8602, Japan

2. Theoretical and Physical Chemistry Institute, National Hellenic Research Foundation, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece

3. Department of Pathology and Biological Responses, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan

4. Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi 466-8550, Japan

5. Innovative Functional Materials Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Nagoya, Aichi 463-8560, Japan

6. International Center for Materials Nanoarchitectonics, National Institute for Materials Science, 1-1 Namiki, Tsukuba 305-0044, Japan

Abstract

We demonstrate that covalent bonding between antibodies and TMDs results in hybrid materials that are remarkably stable. The most notable advantage is that the biosensor devices resist repeated washings without being damaged or losing sensitivity.

Funder

Japan Science and Technology Agency

Japan Society for the Promotion of Science

Core Research for Evolutional Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR06630K

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1. In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges