Aurantiamide-related dipeptide derivatives are formyl peptide receptor 1 antagonists
Author:
Affiliation:
1. Dipartimento di Farmacia – Scienze del Farmaco
2. Università degli Studi di Bari Aldo Moro
3. 70125 Bari
4. Italy
5. Department of Microbiology and Immunology
6. Montana State University
7. Bozeman
8. USA
Abstract
Aurantiamide is a useful scaffold to develop promising FPR1 antagonists capable of inhibiting neutrophil chemotaxis.
Funder
National Institutes of Health
National Institute of Food and Agriculture
Montana Agricultural Experiment Station
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00336C
Reference29 articles.
1. Regulation of inflammation by members of the formyl-peptide receptor family
2. International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the Formyl Peptide Receptor (FPR) Family
3. The Formyl Peptide Receptors: Diversity of Ligands and Mechanism for Recognition
4. N-formylmethionyl peptides as chemoattractants for leucocytes.
5. Pleiotropic roles of formyl peptide receptors
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