Optical control of neuronal firing via photoinduced electron transfer in donor–acceptor conjugates

Author:

Takano Yuta1234,Numata Tomohiro56784,Fujishima Kazuto1234,Miyake Kazuaki9102114,Nakao Kazuya9102114,Grove Wesley David1234,Inoue Ryuji56784,Kengaku Mineko1234,Sakaki Shigeyoshi122134,Mori Yasuo14102114,Murakami Tatsuya1234,Imahori Hiroshi12349ORCID

Affiliation:

1. Institute for Integrated Cell-Material Sciences (WPI-iCeMS)

2. Kyoto University

3. Kyoto 606-8501

4. Japan

5. Department of Physiology

6. Graduate School of Medical Sciences

7. Fukuoka University

8. Fukuoka 814-0180

9. Department of Molecular Engineering

10. Graduate School of Engineering

11. Kyoto 615-8510

12. Fukui Institute for Fundamental Chemistry

13. Kyoto 606-8103

14. Department of Synthetic Chemistry and Biological Chemistry

Abstract

A rationally designed donor–acceptor conjugate efficiently generates a photoinduced charge-separated state in a cellular environment, achieving photoinduction of neuronal firing.

Funder

Ministry of Education, Culture, Sports, Science, and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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