RGD-conjugated two-photon absorbing near-IR emitting fluorescent probes for tumor vasculature imaging

Author:

Yue Xiling1234,Morales Alma R.5678,Githaiga Grace W.1234,Woodward Adam W.1234,Tang Simon1234,Sawada Junko934,Komatsu Masanobu934,Liu Xuan101112134,Belfield Kevin D.141112134

Affiliation:

1. Department of Chemistry

2. University of Central Florida

3. Orlando

4. USA

5. Institute of Chemical Sciences and Engineering

6. Swiss Federal Institute of Technology of Lausanne

7. Lausanne

8. Switzerland

9. Sanford-Burnham Medical Research Institute at Lake Nona

10. Department of Electrical and Computer Engineering

11. New Jersey Institute of Technology

12. University Heights

13. Newark

14. College of Science and Liberal Arts

Abstract

Novel two-photon absorbing fluorescent probes were conjugated with an integrin-targeting peptide, resulting in enhanced tumor vasculature imaging.

Funder

National Science Foundation

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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