Nonconventional chemical inhibitors of microRNA: therapeutic scope

Author:

Jayaraj Gopal Gunanathan12345,Nahar Smita12345,Maiti Souvik12346

Affiliation:

1. Chemical & Systems Biology Unit

2. CSIR-Institute of Genomics and Integrative Biology

3. New Delhi

4. India 110020

5. AcSIR – Academy of Scientific and Innovative Research

6. CSIR-National Chemical Laboratory

Abstract

MicroRNAs (miRNAs) are a class of genomically encoded small RNA molecules (∼22nts in length), which regulate gene expression post transcriptionally. miRNAs are implicated in several diseases, thus modulation of miRNA is of prime importance. Small molecules offer a non-conventional alternative to do so.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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