Intracellular delivery of biomineralized monoclonal antibodies to combat viral infection-Reference-Cited by-同舟云学术

Intracellular delivery of biomineralized monoclonal antibodies to combat viral infection

Published:2016 Issue:9 Volume:52 Page:1879-1882
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Song Zhiyong¹²³⁴⁵,Liu Long⁵⁶⁷⁴⁸,Wang Xiaoyu⁵⁶⁷⁴⁹,Deng Yongqiang⁵⁶⁷⁴,Nian Qinggong⁵⁶⁷⁴,Wang Guangchuan⁵⁶⁷⁴⁹,Zhu Shunya⁵⁶⁷⁴,Li Xiaofeng⁵⁶⁷⁴¹⁰,Zhou Hangyu¹²³⁴⁵,Jiang Tao⁵⁶⁷⁴¹⁰,Xu Xurong¹²³⁴⁹,Tang Ruikang¹²³⁴⁹,Qin Chengfeng⁵⁶⁷⁴⁸

Affiliation:

1. Center for Biomaterials and Bioparthways Department of Chemistry

2. Zhejiang University

3. Hangzhou

4. P. R. China

5. Department of Virology

6. Beijing Institute of Microbiology and Epidemiology

7. Beijing

8. Anhui Medical University

9. Qiushi Academy for Advanced Studies Zhejiang University

10. State Key Laboratory of Pathogen and Biosecurity

Abstract

Conventional therapeutic monoclonal antibodies (mAbs) are invalid for intracellular viruses but by using in situ biomineralization treatment, they can be successfully delivered into cells to inhibit intracellular viral replication.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C5CC09252C

Reference35 articles.

1. Intracellular antibodies and challenges facing their use as therapeutic agents

2. Upping the ante on antibodies

3. Intracellular neutralization of a virus using a cell-penetrating molecular transporter

4. Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus

5. Engineered antibodies

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