Controlled delivery of 5-fluorouracil from monodisperse chitosan microspheres prepared by emulsion crosslinking

Author:

Wan Tong1,Zhang Qianqian1,Jin Guocheng2,Xu Shiai13ORCID

Affiliation:

1. School of Materials Science and Engineering, East China University of Science and Technology, Shanghai 200237, China

2. Shanghai Flowridge Material Technology Co., Ltd, Shanghai 201318, China

3. School of Chemical Engineering, Qinghai University, Xining 810016, China

Abstract

This work aims to determine the optimal conditions for emulsion cross-linking of chitosan (CHS) with various molecular weights using glutaraldehyde as a cross-linking agent to produce 5-fluorouracil-loaded CHS microspheres (5-FU/CHS).

Publisher

Royal Society of Chemistry (RSC)

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