Quinoline-based Schiff bases as possible antidiabetic agents: ligand-based pharmacophore modeling, 3D QSAR, docking, and molecular dynamics simulations study-Reference-Cited by-同舟云学术

Quinoline-based Schiff bases as possible antidiabetic agents: ligand-based pharmacophore modeling, 3D QSAR, docking, and molecular dynamics simulations study

Published:2024 Issue: Volume: Page:
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Ranade Shriram D.¹^ORCID,Alegaon Shankar G.¹^ORCID,Khatib Nayeem A.²^ORCID,Gharge Shankar¹^ORCID,Kavalapure Rohini S.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, KLE College of Pharmacy, Belagavi, KLE Academy of Higher education and Research, Belagavi – 590010, Karnataka, India

2. Department of Pharmacology, KLE College of Pharmacy, Belagavi, KLE Academy of Higher education and Research, Belagavi – 590010, Karnataka, India

Abstract

α-Glucosidase enzyme inhibition is a legitimate approach to combat type 2 diabetes mellitus as it manages to control postprandial hyperglycemia.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/MD/D4MD00344F

Reference41 articles.

1. Pathophysiology of Type 2 Diabetes Mellitus

2. IDFDiabetes Atlas , International Diabetes Federation , Brussels, Belgium , 10th edn, 2021 , https://www.diabetesatlas.org (Accessed 2024)

3. Type II diabetes mellitus: a review on recent drug based therapeutics

4. Exploring New Drug Targets for Type 2 Diabetes: Success, Challenges and Opportunities

5. Antidiabetic Medicinal Plants as a Source of Alpha Glucosidase Inhibitors

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