Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors-Reference-Cited by-同舟云学术

Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors

Published:2019 Issue:50 Volume:9 Page:28961-28986
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Jiang Xiangyi¹²³⁴⁵^ORCID,Wu Gaochan¹²³⁴⁵^ORCID,Zalloum Waleed A.⁶⁷⁸⁹¹⁰,Meuser Megan E.¹¹¹²¹³¹⁴,Dick Alexej¹¹¹²¹³¹⁴,Sun Lin¹²³⁴⁵,Chen Chin-Ho¹⁵¹⁶¹⁷¹⁴,Kang Dongwei¹²³⁴⁵^ORCID,Jing Lanlan¹²³⁴⁵,Jia Ruifang¹²³⁴⁵,Cocklin Simon¹¹¹²¹³¹⁴,Lee Kuo-Hsiung¹⁸¹⁹²⁰²¹¹⁴^ORCID,Liu Xinyong¹²³⁴⁵,Zhan Peng¹²³⁴⁵

Affiliation:

1. Department of Medicinal Chemistry

2. Key Laboratory of Chemical Biology (Ministry of Education)

3. School of Pharmaceutical Sciences

4. Shandong University

5. Ji'nan

6. Department of Pharmacy

7. Faculty of Health Science

8. American University of Madaba

9. Amman

10. Jordan

11. Department of Biochemistry & Molecular Biology

12. Drexel University College of Medicine

13. Philadelphia

14. USA

15. Duke University Medical Center

16. Surgical Oncology Research Facility

17. Durham

18. Natural Products Research Laboratories

19. Eshelman School of Pharmacy

20. University of North Carolina

21. Chapel Hill

Abstract

Novel phenylalanine derivatives were discovered as HIV-1 capsid protein inhibitors via “click reaction”. Most of them exhibited remarkable anti-HIV-1 activity.

Funder

National Natural Science Foundation of China

National Institute of Allergy and Infectious Diseases

Shandong University

Key Technology Research and Development Program of Shandong

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA05869A

Reference42 articles.