The Mukaiyama type aldol reaction for the synthesis of trans-2,6-disubstituted tetrahydropyrans: synthesis of diospongin A and B

Author:

Bharath Yada12345,Choudhury Utkal Mani12345,Sadhana N.1234,Mohapatra Debendra K.12345ORCID

Affiliation:

1. Department of Organic Synthesis and Process Chemistry

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad-500007

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

The synthesis of 2,6-trans-disubstituted tetrahydropyrans following the Mukaiyama type aldol reaction through C–C bond formation demonstrates the practicality of this protocol in the total synthesis of diospongin A and B.

Funder

Science and Engineering Research Board

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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