A general approach to the synthesis of 5-S-functionalized pyrimidine nucleosides and their analogues-Reference-Cited by-同舟云学术

A general approach to the synthesis of 5-S-functionalized pyrimidine nucleosides and their analogues

Published:2014 Issue:30 Volume:12 Page:5634-5644
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kananovich Dzmitry G.¹²³,Reino Alli¹²³,Ilmarinen Kaja¹²³,Rõõmusoks Marko¹²³,Karelson Mati⁴⁵⁶,Lopp Margus¹²³

Affiliation:

1. Tallinn University of Technology

2. Department of Chemistry

3. Tallinn, Estonia

4. Tartu University

5. Institute of Chemistry

6. 50411 Tartu, Estonia

Abstract

A palladium-catalyzed C–S coupling reaction has been used as a key step for the introduction of S-functionality at the C-5 position of the cytosine and uracil nucleosides and their analogues.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00597J

Reference33 articles.

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2. Effect of increasing thiolation of the polycytidylic acid strand of poly I:poly C on the α, β and γ interferon-inducing properties, antiviral and antiproliferative activities

3. Synthesis of 5-Mercaptocytosine Nucleosides and Nucleotides

4. An easy access to 5-mercaptopyrimidine nucleosides through one-step synthesis of 5-thiocyanato-uridine and -2′-deoxyuridine

5. Synthesis, chemistry, and biological activity of 5-thiocyanatopyrimidine nucleosides as potential masked thiols

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