A cooperative-binding split aptamer assay for rapid, specific and ultra-sensitive fluorescence detection of cocaine in saliva
Author:
Affiliation:
1. Department of Chemistry and Biochemistry
2. Florida International University
3. Miami
4. USA
5. Department of Chemistry
6. Capital Normal University
7. Beijing
8. China
Abstract
A fluorescence assay based on a split aptamer featuring a cooperative-target-binding mechanism performs one-step, rapid detection of as low as 50 nM in 10% saliva without signal amplification.
Funder
National Institute of Justice
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/SC/C6SC01833E
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