Fluorescence and ratiometric photoacoustic imaging of endogenous furin activity via peptide functionalized MoS2 nanosheets-Reference-Cited by-同舟云学术

Fluorescence and ratiometric photoacoustic imaging of endogenous furin activity via peptide functionalized MoS2 nanosheets

Published:2021 Issue:24 Volume:9 Page:8313-8322
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Li Xiao¹,Xiu Weijun¹,Xiao Hang¹,Li Yuqing¹,Yang Kaili¹,Yuwen Lihui¹^ORCID,Yang Dongliang²,Weng Lixing³,Wang Lianhui¹^ORCID

Affiliation:

1. Key Laboratory for Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Centre for Advanced Materials (SICAM), Nanjing University of Posts and Telecommunications, 9 Wenyuan Road, Nanjing 210023, China

2. School of Physical and Mathematical Sciences & Institute of Advanced Materials (IAM), Nanjing Tech University, Nanjing 211800, China

3. School of Geography and Biological Information, Nanjing University of Posts and Telecommunications, Nanjing 210023, China

Abstract

Cleavage of the peptide linker on nanoprobes by furin leads to fluorescence recovery and subsequently the more rapid clearance of small Cy7 molecules from tumor tissues than large MoS2 NSs, which realizes dual-mode detection of furin in vivo.

Funder

National Key Research and Development Program of China

Jiangsu Provincial Key Research and Development Program

Natural Science Foundation of Jiangsu Province

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM01410B

Reference41 articles.