Fluorinated dendrimer for TRAIL gene therapy in cancer treatment
Author:
Affiliation:
1. Shanghai Key Laboratory of Regulatory Biology
2. School of Life Sciences
3. East China Normal University
4. Shanghai
5. P. R. China
Abstract
The transfection of tumor necrosis factor-related apoptosis-inducing ligand gene by using fluorinated dendrimer is highly efficient and low toxic, resulting in efficient killing of cancer cells in vitro and suppressing tumor growth in vivo.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2016/TB/C5TB02712H
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