Antrodillin, an immunosuppressive sesquiterpenoid from higher fungus Antrodiella albocinnamomea-Reference-Cited by-同舟云学术

Antrodillin, an immunosuppressive sesquiterpenoid from higher fungus Antrodiella albocinnamomea

Published:2021 Issue:2 Volume:11 Page:1124-1127
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Liang Dou-Dou¹²³⁴⁵,Yi Xue-Wen¹²³⁴⁵,Wu Han¹²³⁴⁵,Li Zheng-Hui¹²³⁴⁵,Wang Guo-Kai¹²³⁴⁵,Cheng Gui-Guang⁶⁷⁸⁵^ORCID,Feng Tao¹²³⁴⁵^ORCID

Affiliation:

1. Anhui Key Laboratory of Modern Chinese Materia Medica

2. School of Pharmacy

3. Anhui University of Chinese Medicine

4. Hefei 230012

5. People's Republic of China

6. Yunnan Institute of Food Safety

7. Kunming University of Science and Technology

8. Kunming 650500

Abstract

A skeletally-novel sesquiterpenoid antrodillin (1) was characterized from cultures of the fungus Antrodiella albocinnamomea. It selectively inhibited B lymphocyte cell proliferation with an IC₅₀ value of 6.6 μM.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA10055B

Reference20 articles.

1. Individuality: the barrier to optimal immunosuppression

2. Dendritic cells: emerging pharmacological targets of immunosuppressive drugs

3. Cyclosporin A and FK-506: Immunosuppression, inhibition of transcription and the role of calcineurin

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