Niacin/β-hydroxybutyrate regulates milk fat and milk protein synthesis <i>via</i> the GPR109A/G<sub>i</sub>/mTORC1 pathway-Reference-Cited by-同舟云学术

Niacin/β-hydroxybutyrate regulates milk fat and milk protein synthesis via the GPR109A/G_i/mTORC1 pathway

Published:2023 Issue:6 Volume:14 Page:2642-2656
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Chen Jiaming¹^ORCID,Lin Tongbin¹,Zhang Shuchang¹,Yue Xianhuai¹,Liu XingHong¹,Wu Caichi¹,Liang Yunyi¹,Zeng Xiangfang²,Ren Man³,Chen Fang¹⁴⁵,Guan Wutai¹⁴⁵^ORCID,Zhang Shihai¹⁴⁵^ORCID

Affiliation:

1. Guangdong Province Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou, 510642, China

2. State Key Laboratory of Animal Nutrition, Ministry of Agriculture and Rural Affairs Feed Industry Center, China Agricultural University, Beijing, China

3. College of Animal Science, Anhui Science and Technology University, Anhui Provincial Key Laboratory of Animal Nutritional Regulation and Health, Fengyang, China

4. College of Animal Science and National Engineering Research Center for Breeding Swine Industry, South China Agricultural University, Guangzhou 510642, China

5. Guangdong Laboratory for Lingnan Modern Agriculture, South China Agricultural University, Guangzhou, China

Abstract

Both niacin and BHBA promote milk fat and milk protein synthesis with the activation of GPR109A/mTORC1 signaling in mammary gland epithelial cells.

Funder

National Key Research and Development Program of China

Basic and Applied Basic Research Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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