Gemini lipid nanoparticle (GLNP)-mediated oral delivery of TNF-α siRNA mitigates gut inflammation <i>via</i> inhibiting the differentiation of CD4<sup>+</sup> T cells-Reference-Cited by-同舟云学术

Gemini lipid nanoparticle (GLNP)-mediated oral delivery of TNF-α siRNA mitigates gut inflammation via inhibiting the differentiation of CD4⁺ T cells

Published:2022 Issue:39 Volume:14 Page:14717-14731
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Verma Priyanka¹,Arora Amit²,Rana Kajal¹^ORCID,Mehta Devashish¹^ORCID,Kar Raunak³,Verma Vikas²,Srikanth C. V.⁴,Patil Veena S.³,Bajaj Avinash¹^ORCID

Affiliation:

1. Laboratory of Nanotechnology and Chemical Biology, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone Faridabad-Gurgaon Expressway, Faridabad-121001, India

2. Department of Chemistry, Guru Jambheshwar University of Science & Technology, Hisar-125001, India

3. National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi,-110067, India

4. Laboratory of Gut Inflammation and Infection Biology, Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone Faridabad-Gurgaon Expressway, Faridabad-121001, India

Abstract

Gemini lipid nanoparticle (GLNP)-mediated oral delivery of TNF-α siRNA mitigates gut inflammation via inhibiting the differentiation of CD4+ T cells.

Funder

Regional Centre for Biotechnology

National Institute of Immunology

Department of Biotechnology, Ministry of Science and Technology

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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