Comparative efficacy of vanilloids in inhibiting toll-like receptor-4 (TLR-4)/myeloid differentiation factor (MD-2) homodimerisation-Reference-Cited by-同舟云学术

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Comparative efficacy of vanilloids in inhibiting toll-like receptor-4 (TLR-4)/myeloid differentiation factor (MD-2) homodimerisation

Published:2018 Issue:6 Volume:9 Page:3344-3350
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Mai Chun-Wai¹²³⁴⁵^ORCID,Kang Yew Beng¹²³⁴⁵,Hamzah Ahmad Sazali⁶⁷⁸⁵,Pichika Mallikarjuna Rao¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. School of Pharmacy

3. International Medical University (IMU)

4. Kuala Lumpur

5. Malaysia

6. Universiti Teknologi MARA Shah Alam Selangor Malaysia

7. Institute of Science

8. Shah Alam

Abstract

Vanilloids in commonly eaten foods are anti-inflammatory via inhibition of TLR-4/MD-2 homodimerisation. 6-Shogaol is the most potent vanilloid.

Funder

International Medical University

Malaysia TORAY Science Foundation

Kementerian Sains, Teknologi dan Inovasi

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO00136G

Reference25 articles.

1. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

2. Pattern Recognition Receptors and Inflammation

3. Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis

4. Targeting TLR/IL-1R Signalling in Human Diseases

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