Benzene-glycol nucleic acid (BGNA)–DNA chimeras: synthesis, binding properties, and ability to elicit human RNase H activity-Reference-Cited by-同舟云学术

Benzene-glycol nucleic acid (BGNA)–DNA chimeras: synthesis, binding properties, and ability to elicit human RNase H activity

Published:2017 Issue:41 Volume:7 Page:25378-25386
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Niwa Nazuki¹²³⁴,Shimizu Saki⁵⁶⁷⁸⁴,Maeda Yusuke¹²³⁴,Hiroak Hidekazu⁵⁶⁷⁸⁴,Ueno Yoshihito¹²³⁴⁹

Affiliation:

1. Course of Applied Life Science

2. Faculty of Applied Biological Sciences

3. Gifu University

4. Japan

5. Division of Structural Biology

6. Graduate School of Pharmaceutical Sciences

7. Nagoya University

8. Nagoya

9. United Graduate School of Agricultural Science

Abstract

This paper describes the synthesis and properties of benzene-glycol nucleic acid (BGNA)–DNA chimeras containing four nucleoside analogs – thymidine, cytidine, adenosine, and guanosine – with a base-benzene-glycol structure.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA03896H

Reference12 articles.

1. Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide.

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3. Oligonucleotide Conjugates as Potential Antisense Drugs with Improved Uptake, Biodistribution, Targeted Delivery, and Mechanism of Action

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