Cyanidin 3-O-glucoside prevents the development of maladaptive cardiac hypertrophy and diastolic heart dysfunction in 20-week-old spontaneously hypertensive rats

Author:

Aloud Basma Milad12345,Raj Pema12345,McCallum Jason644,Kirby Chris644,Louis Xavier Lieben734,Jahan Fahmida89101112,Yu Liping53464,Hiebert Brett131434,Duhamel Todd A.15161723,Wigle Jeffrey T.1823419,Blewett Heather12345,Netticadan Thomas12345ORCID

Affiliation:

1. Department of Physiology and Pathophysiology

2. University of Manitoba

3. Winnipeg

4. Canada

5. Canadian Centre for Agri-Food Research in Health and Medicine

6. Agriculture and Agri-Food

7. Richardson Center for Functional Food and Nutraceuticals

8. Translational Nutrition Biology

9. Department of Health Sciences and Technology

10. Switzerland Federal Institute of Technology

11. Zurich

12. Switzerland

13. Cardiac Sciences Program

14. Winnipeg Regional Health Authority

15. Health

16. Leisure and Human Performance Research Institute

17. Faculty of Kinesiology and Recreation Management

18. Department of Biochemistry and Medical Genetics

19. Institute of Cardiovascular Sciences

Abstract

Cyanidin 3-O-glucoside prevents ET1-induced cardiomyocytes hypertrophy and fibroblast differentiationin vitroand cardiac abnormalities in SHR.

Funder

Agriculture and Agri-Food Canada

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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